Pyxis is a software for ion mobility mass spectrometry imaging (IMS-MSI), that supports both untargeted and targeted data analysis, distributed as desktop application. The workflow supported by Pyxis covers all the steps required for IMS-MSI data analysis: raw data processing, histological coregistration, image and mobilogram visualization, statistical analysis and automated metabolites identification.
Features
Data import
- Bruker timsTOF flex
- Waters SELECT SERIES Cyclic IMS
Data Analysis
- Peak detection and pre-processing, both on the m/z and mobility domains
- Spectral and image analysis
- Statistical Analysis: Segmentation, PCA, Colocalization
- Annotation and identification
Image Analysis
- Denoise, contrast enhancement, normalization
- Single and overlaid ion density images visualization
- Coregistration
- Possibility to cluster and visualize isobars images with different mobility values
Automation
- Background processing of computational intensive tasks
- Optimized and parallelized algorithms
System requirements
- Microsoft® Windows® 10 64 Bit operating system
- At least 32 GB of RAM (or superior)
- SATA III SSD 2T (or superior)
- Intel® Core™ i7 processor or Intel® Xeon® processor